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Keep it eco Recent technological advances have brought improvements to cold chain logistics – but with aviation remaining a major part of pharma supply chains, the industry is under pressure...
Powder analysis: The next level In pharmaceutical manufacturing, many critical parameters determine the successful formulation of powders for oral dosage, among them flowability, solubility, consistency, purity...
Tracking safety As one of the most regulated industries on earth, safety and effectiveness of medication is of the utmost importance across global pharma. One way of ensuring safety is traceability...
Patch things up Researchers from the University of North Carolina have created a new drug delivery system called the Spatiotemporal On-Demand Patch (SOP), which can receive wireless commands from...
Dealing with rare diseases Globally, there are over 300 million patients living with rare diseases, but they often lack appropriate drug delivery devices. Many are provided with standard syringes and vials that...
Revolution in pharma The adoption of Pharma 4.0 technology is accelerating as pharmaceutical companies look to optimise processes, reduce costs, improve quality and foster innovation. But many are being...
Labelling for life We don’t often think of labelling as a risky behaviour, but incorrect information can be detrimental at every stage of the clinical trial supply chain, not to mention for patients once...
Oncology's data puzzle Oncology trials generate huge volumes of data from many different sources, and they do so over long periods of time. The payoff of demonstrating an effective therapy for cancer can...
Innovations and hurdles The discovery and development of CAR T-cell therapies will go down in the annals of medical history. But while remarkably effective against a range of cancers, these advanced...
Centralised submission The change from the Clinical Trials Directive to the Clinical Trials Regulation in Europe has been long and slow, but now that the new regime is in place there is one burning question...
The shifting roles of CROs The dial has been shifting for some time now on how much research and development work is carried out in-house by pharmaceutical companies. While outsourcing in the industry was...
Innovation in inhalation Blue and brown inhalers have become synonymous with asthma, but inhaling doses of medication is something we might see more of as drug developers look at inhalation as a strategy to...
Polysorbates and their alternatives Unlike small-molecule drugs – which are typically chemically synthesised – biologics are large, complex molecules derived from living organisms. The downside of this is that these...
A green future for peptides The use of peptides has been growing at pace during the past couple of decades, owing to their high likelihood of regulatory approval and probability of success in clinical trials....
Air or sea? The majority of the world’s pharmaceuticals are transported by sea freight, owing to its substantially lower cost. The predominant reason for using air freight instead is urgency, but...
The viscosity problem It’s no surprise that the physical characteristics of an injectable substance will have a bearing on how it functions inside the body. But exactly what those effects are may not be...
The right selection A large portion of pharmaceutical manufacturing happens outside of the premises of the companies who brand and sell drug products. According to some sources, it could be as high...
Sustainability in mind Reaching carbon neutrality by 2040 will require a lot more of pharmaceutical companies than reducing CO2 emissions, water and electricity. Coordinated effort is required...
Pharma 4.0 Tools that take advantage of advances in AI and machine learning, alongside other burgeoning technologies, are often marked with a ‘4.0’ suffix to denote that it’s part of the...
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